Project

1)    Targeting drug resistant cancer stem cells by combinational delivery of Paclitaxel and Quercetin/Zerumbone in breast cancer

Jammu and Kashmir Science and Technology Innovation Council (Srinagar, Jammu and Kashmir, IN)  Grant number: JKST&IC/SRE/885-87

    

Papers

1)    Identification and analysis of dysregulated fatty acid metabolism genes in breast cancer subtypes. DOI: 10.1007/s12032-022-01861-2 

2)    Expression Pattern and Prognostic Significance of Chemokines in Breast cancer: An Integrated Bioinformatics Analysis. DOI: 10.1016/j.clbc.2022.04.008

3)    Adapalene and Doxorubicin Synergistically Promote Apoptosis of TNBC Cells by Hyperactivation of the ERK1/2 Pathway Through ROS Induction DOI: 10.3389/fonc.2022.938052

4)    Adapalene inhibits the growth of triple-negative breast cancer cells by S-phase arrest and potentiates the antitumor efficacy of GDC-0941 DOI: 10.3389/fphar.2022.958443

5)    Expression patterns and therapeutic implications of CDK4 across multiple carcinomas: a molecular docking and MD simulation study. DOI: 10.1007/s12032-022-01779-9

6)    Cyclin-dependent kinases in breast cancer: expression pattern and therapeutic implications. DOI: 10.1007/s12032-022-01731-x

7)    Targeting cyclin-dependent kinase 1 (CDK1) in cancer: molecular docking and dynamic simulations of potential CDK1 inhibitors. DOI: 10.1007/s12032-022-01748-2 (CDK1)

8)    Cryptolepine Targets TOP2A and Inhibits Tumor Cell Proliferation in Breast Cancer Cells - An In vitro and In silico Study. DOI: 10.2174/1871520622666220419135547

9)    Expression pattern and prognostic significance of CDKs in breast cancer: An integrated bioinformatic study. DOI: 10.3233/cbm-210186

10) Expression pattern and prognostic significance of baculoviral inhibitor of apoptosis repeat-containing 5 (BIRC5) in breast cancer: A comprehensive analysis. DOI: 10.1016/j.adcanc.2022.100037 (BIRC5)

11) The tumor microenvironment as driver of stemness and therapeutic resistance in breast cancer: New challenges and therapeutic opportunities. DOI: 10.1007/s13402-021-00634-9

12) An insight into the cancer stem cell survival pathways involved in chemoresistance in triple-negative breast cancer. DOI: 10.2217/fon-2021-0172

13) Tumor microenvironment promotes breast cancer chemoresistance. DOI: 10.1007/s00280-020-04222-w

14) Rising trends of Cancers in Kashmir valley: Distribution Pattern, Incidence and Causes.

15) Targeting Different Pathways Using Novel Combination Therapy in Triple Negative Breast Cancer. DOI: 10.2174/1570163817666200518081955

16) Double-crosser of the Immune System: Macrophages in Tumor Progression and Metastasis. DOI: 10.2174/1573395515666190611122818